Skip to content

Epigenetic Station

Epigenetic Resource and Protocol Centre

Menu
  • Home
  • Sequencing of Sodium
  • Treatment of Cells
  • DNA METHYLATION
  • DNA Methylation
Menu

Month: December 2022

Compare antibodies lab reagents for research

Posted on December 29, 2022

Suppliers for Lab antibodies Our used rec. in Pubmed. https://rusbiolink.com/

Read more

Compare ELISA lab reagents for research

Posted on December 29, 2022

Suppliers for Lab Assays Our used antibodies in Pubmed.

Read more

Chromosomes

Posted on December 29, 2022

Packing of DNA is required are DNA molecules in eukaryotes is very large. DNA therefore packs itself up into structures referred to as chromosomes. This allows DNA to be stored within the nucleus of cells. The process is simple, with DNA being the lowest for of storage, moving to nucleosomes, which is protein interacting with…

Read more

GENOMIC IMPRINTING

Posted on December 29, 2022

Genomic imprinting affects several dozen mammalian genes and results in the expression of those genes from only one of the two parental chromosomes (Reik and Walter, 2001). These mammalian genes function differently depending on whether they came from the mother or the father (Susani et al., 1984; McGrath and Solter, 1984). A key molecular mechanism…

Read more

Insulators and the Loop Domain Model

Posted on December 29, 2022

In the loop domain model, inactive DNA is heterchromatin, with methylated DNA and hypoacetylated histones. Active DNA, is euchromatin, and has hyperacetylated histones and unmethylated DNA. Chromatin fibers are attached within the nucleus to nuclear matrix component structures through specific DNA binding proteins. This creates ‘loop domains’ within the nucleus, as it compartmentalizes sections of…

Read more

Histone Code

Posted on December 29, 2022

Histones are key regulators of gene expression, through numerous well-known chemical modifications. These include acetylation, phosphorylation, methylation, and ubiquitylation. For example, methylating and/or acetylating specific lysine residues of the nucleosomal cores of histones, such as lysine8, alter the chromatin structure, through interacting with the methylation machinery, and gene expression (1). DNA Methylation Machinery, Histone Deacetylases…

Read more

Repetitive Sequences and Epigenetics

Posted on December 29, 2022

In comparison to CpG islands, which are found in the regulatory regions of genes, and are prime importance in the transcription of the regulators of cell growth and death, repetitive sequences, also known as endoparasitic sequences, which are transposable elements, inserting themselves into any sequence they please throughout the genome, are thankfully in normal cells,…

Read more

CpG Island

Posted on December 29, 2022

Cytosine methylation of DNA at CpG dinucleotides is the most well-known epigenetic change. Less than 10% of all cytosines are methylated in the human genome (1). These CpG dinucleotides are also not found randomly throughout the genome, but in finite areas, specifically clustered at the 5′ region of genes, in the promoter, untranslated region, and…

Read more

Gene Regulation

Posted on December 29, 2022

DNA Transcription – Nuclear compartmentalization, chromatin remodelling, recruitment of transcription machinery, transcription initiation, elongation, termination andpolyadenylation Splicing of mRNA Transport of mRNA out of Nucleus to Cytoplasm Localization and/or Degradation of mRNA Translation – localization, cleavage, degradation, covalent modification

Read more

monoclonal Lab Reagents for Research

Posted on December 28, 2022

Promoted Lab ELISAs Our used antibodies in Pubmed.

Read more

Recent Posts

  • Compare antibodies lab reagents for research
  • Compare ELISA lab reagents for research
  • Chromosomes
  • GENOMIC IMPRINTING
  • Insulators and the Loop Domain Model

Recent Comments

No comments to show.

Archives

  • December 2022

Categories

  • Blog
  • Uncategorized
©2023 Epigenetic Station | WordPress Theme by Superbthemes.com