Epigenetic Methylation Station

Your source for information, protocols, and bioinformatics about epigenetics and DNA methylation.

Month: August 2018

CpG Island 05Aug

CpG Island

CpG Island and Epigenetics: Cytosine methylation of DNA at CpG dinucleotides is the most well known epigenetic change. Less than 10% of all cytosines are methylated in the human genome (1). These CpG dinucleotides are

Gene Regulation 05Aug

Gene Regulation

DNA Transcription – Nuclear compartmentalization, chromatin remodelling, recruitment of transcription machinery, transcription initiation, elongation, termination andpolyadenylation Splicing of mRNA Transport of mRNA out of Nucleus to Cytoplasm Localization and/or Degradation of mRNA Translation – localization,

X-Chromosome Inactivation 02Aug

X-Chromosome Inactivation

The X chromosome is a sex chromosome found in humans, fruit flies and certain other animals where the male is the heterogametic sex. In the XY set of sex chromosomes, the female has two X

Genomic Imprinting 01Aug

Genomic Imprinting

Genomic imprinting affects several dozen mammalian genes and results in the expression of those genes from only one of the two parental chromosomes (Reik and Walter, 2001). These mammalian genes function differently depending on whether